博士,教授,博导;福建省引进高层次人才(境外C类),福建省级高层次人才(C类),英国威廉希尔公司金山学者青年学术新秀;福建省食用菌学会理事、福建省食用菌行业协会理事、福建省生物医学工程学会理事、福建省微生物学会药用真菌专业委员会副主任委员、中国菌物学会桑黄产业分会理事,福建省食用菌产业技术创新联盟副秘书长;2011.2-2012.11 美国堪萨斯大学医学中心博士后、2012.12-2014.10美国北卡罗莱纳农业技术州立大学博士后、2016.11-2017.11美国北卡罗莱纳中央大学国家公派访问学者。
主要从事食用菌领域的教学与科学研究工作,致力于解析食用菌营养与人类健康关系,重点开展蛹虫草、桑黄等药用真菌的保健功能物质基础研究,挖掘其活性成分的抗癌分子转导机制;当前,主持国家级、省部级、横向课题等项目10多个;主持省地方标准1项;以(含共同)第一作者或通讯作者发表SCI论文24篇和中文论文48篇;第一发明人授权发明专利5项;第一完成人鉴定食用菌新品种1个;承担普通真菌学、食用菌栽培学等课程,教改项目1个,教改论文4篇。
联系邮箱:fujunsheng81@163.com
一、当前兴趣研究
1、蛹虫草真菌资源的挖掘与产业化应用技术研究;
2、虫草素纳米药物递送系统开发与抗肿瘤机制研究;
3、桑黄高产孢子粉新种质创制及高效栽培技术研究;
4、桑黄黑色素的制备、功效评价与产品开发。
二、近3年发表文章
1. Hu, Xin et al. Fermented Lentinus edodes extract containing alpha-glucan ameliorates Concanavalin A-induced autoimmune hepatitis in mice. Food Science and Human Wellness (2024),accepted.
2. Xiaomin Li, Qing Liu, Songyu Xie, Xiaoping Wu, Junsheng Fu*, Mechanism of action of cordycepin in the treatment of hepatocellular carcinoma via regulation of the Hippo signaling pathway, Food Science and Human Wellness, Volume 13, Issue 2, 2024, Pages 1040-1054, https://doi.org/10.26599/FSHW.2022.9250090.
3. Yuan Y, Wu F, Zhang F, Li X, Wu X, Fu J*. Hepatoenteric Protective Effect of Melanin from Inonotus hispidus on Acute Alcoholic Liver Injury in Mice. Mol Nutr Food Res. 2023 Jul;67(14):e2200562. doi: 10.1002/mnfr.202200562. Epub 2023 May 25. PMID: 37162033.
4. Li X, Wu W, Zhang F, Hu X, Yuan Y, Wu X, Fu J*. Differences between water-soluble and water-insoluble melanin derived from Inonotus hispidus mushroom. Food Chem X. 2022 Nov 11;16:100498. doi: 10.1016/j.fochx.2022.100498. PMID: 36519091; PMCID: PMC9743160.
5. Xiaomin Li, Wenya Wu, Fenghua Cao, Xin Hu, Xiaoping Wu, Junsheng Fu*, Mechanism of cordycepin enhancing doxorubicin against hepatocellular carcinoma in vitro and in vivo, Journal of Functional Foods, Volume 98, 2022, 105268, https://doi.org/10.1016/j.jff.2022.105268.
6. Wu W, Li X, Qi M, Hu X, Cao F, Wu X, Fu J*. Cordycepin Inhibits Growth and Metastasis Formation of MDA-MB-231 Xenografts in Nude Mice by Modulating the Hedgehog Pathway. Int J Mol Sci. 2022 Sep 8;23(18):10362. doi: 10.3390/ijms231810362. PMID: 36142286; PMCID: PMC9499653.
7. Zhang F, Xu H, Yuan Y, Huang H, Wu X, Zhang J*, Fu J*. Lyophyllum decastes fruiting body polysaccharide alleviates acute liver injury by activating the Nrf2 signaling pathway. Food Funct. 2022 Feb 21;13(4):2057-2067. doi: 10.1039/d1fo01701b. PMID: 35107114.
8. Zhang F, Xue F, Xu H, Yuan Y, Wu X, Zhang J, Fu J*. Optimization of Solid-State Fermentation Extraction of Inonotus hispidus Fruiting Body Melanin. Foods. 2021 Nov 23;10(12):2893. doi: 10.3390/foods10122893. PMID: 34945444; PMCID: PMC8700211.
9. Ruolin Hou, Xin Liu*, Xiaoping Wu, Mingfeng Zheng, Junsheng Fu*, Therapeutic effect of natural melanin from edible fungus Auricularia auricula on alcohol-induced liver damage in vitro and in vivo, Food Science and Human Wellness, Volume 10, Issue 4, 2021, Pages 514-522,https://doi.org/10.1016/j.fshw.2021.04.014.